Posts by: Joana Carvalho

Joana Carvalho

January 15, 2019January 15, 2019

Review Study Supports Ability of Epidiolex to Reduce Seizure Frequency in Dravet, Lennox-Gastaut Patients

News

GW Pharmaceuticals‘ Epidiolex, the first plant-derived cannabidiol medication to be approved by the U.S. Food and Drug Administration, is effective in significantly reducing the frequency of epileptic seizures as an ... Read more

December 13, 2018December 13, 2018

Fintepla Improves Behavioral and Emotional Control in Dravet Patients, Analysis of Phase 3 Trials Shows

News

Zogenix‘s investigational compound Fintepla (fenfluramine HCl oral solution) improves behavioral and emotional control in children and young adults with Dravet syndrome, according to recent data presented at the 72nd American Epilepsy Society ... Read more

November 29, 2018November 29, 2018

Diacomit Add-On Therapy More Effective in Children With Dravet Syndrome Who Carry Pathogenic SCN1A Mutations, Study Shows

News

Diacomit (stiripentol) add-on therapy is more effective in children with Dravet syndrome who have pathogenic (disease-causing) SCN1A mutations than in those with variants of unknown significance and benign SCN1A mutations, a ... Read more

October 18, 2018October 18, 2018

GABAergic System Impairment Worsens Seizures in Dravet Patients, Study Reveals

News

For the first time, researchers have described a dysfunction in the brain’s GABAergic system that could increase the frequency and severity of epileptic seizures in patients with Dravet syndrome. The ... Read more

September 27, 2018September 27, 2018

Glucose Uptake is Significantly Decreased in the Brains of Dravet Syndrome Children, Study Shows

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For the first time, positron emission tomography (PET) scans revealed a significant decrease in the amount of glucose uptake in the brains of children with Dravet syndrome. Interestingly, this reduction ... Read more

September 20, 2018September 20, 2018

Genetic Mutations in SCN1A Put Dravet Patients at Risk of SUDEP, Study Shows

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Researchers found that patients with Dravet syndrome are at higher risk of suffering sudden unexpected death in epilepsy (SUDEP) due to genetic mutations in the SCN1A gene that predispose them to heart ... Read more

September 11, 2018September 11, 2018

Early Diagnosis, Anti-epileptic Treatment Benefits 3 Children with Dravet, Autism, Study Reports

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Early diagnosis followed by treatment with anti-epileptic medications reduced the frequency of seizures and behavioral problems in three children with both Dravet syndrome and autism spectrum disorder (ASD), a study ... Read more

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