Posts by: Joana Carvalho

Joana Carvalho

May 10, 2019May 14, 2019

#AANAM – Epidiolex Reduces Frequency of Seizures in Children with Dravet Syndrome, Phase 3 Trial Shows

News

GW Pharmaceuticals‘ Epidiolex, the first plant-derived cannabidiol (CBD) medication to be approved by the U.S. Food and Drug Administration (FDA), reduces the frequency of epileptic seizures when used as an add-on therapy ... Read more

April 23, 2019April 23, 2019

Diacomit Tops List of Add-on Therapies to Control Epileptic Seizures in Children With Dravet, Review Study Says

News

Compared with its competitors, Diacomit (stiripentol) remains in the top position as an add-on therapy to control epileptic seizures in young children with Dravet syndrome, or in those who are affected ... Read more

April 16, 2019April 16, 2019

FDA Refuses New Drug Application for Zogenix’s Fintepla (ZX008)

News

The U.S. Food and Drug Administration (FDA) refused the New Drug Application (NDA) for Fintepla (ZX008), Zogenix‘s investigational anti-seizure therapy for patients with Dravet syndrome. According to statements from ... Read more

April 9, 2019April 9, 2019

Dravet Syndrome Patients Exhibit Variety of Gait Alterations, Review Finds

News

A wide variety of gait alterations have been reported for patients with Dravet syndrome, but the most common seems to be the crouch gait, a posture in which patients ... Read more

April 2, 2019April 2, 2019

Anti-seizure Effects of Cannabinoids May Benefit Some Neurological Disorders But Not Others, Review Study Says

News

Despite the promising anti-seizure effects of cannabinoids in children with Dravet syndrome and Lennox-Gastaut syndrome, more research is needed to understand how these compounds work and their potential benefits for ... Read more

March 14, 2019March 14, 2019

Multimodal Analysis is Best to Categorize SCN1A Genetic Variants, Study Says

News

Multimodal analysis that incorporates data obtained from different methodologies seems to be the best approach to build a solid classification system for SCN1A genetic variants associated with Dravet syndrome, ... Read more

March 5, 2019March 5, 2019

Positive Outcomes can be Achieved Via Early Diagnosis, Adequate Treatment and Follow-up, Case Report Says

News

A deep understanding of the natural history of Dravet syndrome, an early diagnosis, carefully considered treatment, and regular follow-up care are crucial to attain positive clinical outcomes, according to a case ... Read more

February 19, 2019February 19, 2019

Latest Genetic Sequencing Techniques Reveal New Disease Mutations Associated With Epilepsy and Dravet Syndrome

News

Next-generation sequencing techniques have revealed that genetic mutations in the KCND3 gene may be responsible for more types of epilepsy than previously thought, and new candidate genes associated with Dravet syndrome have ... Read more

February 14, 2019February 19, 2019

Zogenix Submits Marketing Applictions for Fintepla to Treat Seizures in Dravet

News

Zogenix has announced the submission of a New Drug Application (NDA) to the U.S. Food and Drug Administration (FDA) and a Marketing Authorization Application (MAA) to the European Medicines Agency ... Read more

January 31, 2019January 31, 2019

SCN1A Mutations, Seizures Contribute to Disease Severity in Mouse Model of Dravet Syndrome

News

Mutations in the SCN1A gene and epileptic seizures contribute to disease severity in a mouse model of Dravet syndrome, a study reports. The study, “A two-hit story: Seizures and ... Read more

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