News

Cognitive, physiotherapy common with Dravet, but benefits not clear

Most Dravet syndrome patients utilize various types of therapies beyond medicines to manage the disease, including physiotherapy, occupational therapy, and psychological therapy, according to a recent survey of caregivers and family members in Spain. While survey respondents sometimes found these non-pharmacological interventions to be effective, sizable numbers were less…

Fewer seizures, better behavior seen with STK-001 treatment for Dravet

STK-001, an investigational treatment for children and adolescents with Dravet syndrome, markedly reduced seizure frequency and improved cognition and behavior, according to new findings in Phase 1/2a clinical trials. “The substantial and sustained reductions in seizure frequency and improvements in cognition and behavior observed in our STK-001 clinical studies…

Diacomit may be effective for hard-to-treat seizures outside Dravet

Diacomit (stiripentol), known to help control seizures in people with Dravet syndrome, also may aid those with other childhood disorders marked by hard-to-treat seizures, according to a study out of Spain. “Although further prospective studies are needed, our findings suggest that add-on [Diacomit] may be a therapeutic option for…

Gastrointestinal, eating problems found to be common in Dravet

People with Dravet syndrome due to mutations in the SCN1A gene are more frequently affected by gastrointestinal and eating problems than those with other SCN1A-associated disorders, according to a study from the Netherlands. More than three-quarters of Dravet patients were reported to be experiencing two or more such issues, compared…